Research review: we have not tested this device ourselves. This review combines the maker's own specs and pricing, FDA and veterinary-regulatory context, and the device's own Amazon listing data, checked September 20, 2026.

The Assisi Loop is the device that keeps showing up when you search for a serious, not-a-toy PEMF option for a dog, cat, or horse. It is small, it looks almost too simple for a $329 price tag, and it carries a claim most PEMF products in this market cannot make: an actual FDA clearance history behind its underlying technology. This review covers what the Loop actually is, what "FDA cleared" does and does not mean for a device sold for animals, its full current lineup and pricing, what the evidence supports, and how it stacks up against the rest of the at-home PEMF options.

What the Assisi Loop is

The Assisi Loop delivers targeted Pulsed Electromagnetic Field (tPEMF) therapy through a plastic loop that sits around or near the treatment area, without needing direct skin contact. Zomedica, the veterinary-health company that now owns Assisi Animal Health, describes the mechanism as a micro-current, about one-one-thousandth the strength of a cell phone signal, that stimulates the animal's own nitric-oxide production to trigger its natural anti-inflammatory response.

The current lineup, confirmed on Assisi's own storefront:

Product	What it's for	Price
Assisi LOOP 2.0 (10cm or 20cm)	The original localized device: a single treatment area on a dog, cat, or small/medium horse	$329
Assisi EquiLOOP 2.0 (10cm or 20cm)	The same core device, sized and marketed specifically for horses	$329
LOOP Lounge (Small / Medium / Large)	A padded, bed-style full-body PEMF system (memory-foam pad driven by a controller box) for whole-body coverage rather than one spot	$949 / $1,599 / $1,999
DentaLOOP	A smaller loop shaped for oral and dental use	$149 (device only)

Prices confirmed directly from Assisi's Shopify storefront (shop.assisi.zomedica.com/products.json) on September 20, 2026.

Three things are worth knowing before you buy. First, "Loop" and "EquiLOOP" are the same underlying device at the same $329 price; EquiLOOP is simply sized and marketed for horses, so do not assume the horse version costs more. Second, the LOOP Lounge is a materially different, more expensive product line (a full-body system, not a single loop), and it is the right comparison point against the full equine PEMF blanket systems covered in our PEMF for horses guide, not against the base Loop.

Third, and this changes the cost picture: a Loop is a consumable. Assisi's own FAQ states that "the Assisi LOOP offers approximately 150 15-minute treatments," that "the life of the LOOP depends on the battery," that "at this time, there is no way to recharge or replace the battery," and that one Loop 2.0 "can last anywhere from 3 weeks to 6 months, depending on the condition being treated and the number of treatments required per day." So $329 does not buy a device you keep. It buys roughly 150 sessions, which works out near $2 each, and when the battery is done you buy another unit. That is still far cheaper per session than a $75 to $125 practitioner visit, and Assisi notes you may get more than the stated minimum if you let the Loop rest two hours between treatments, but plan the total cost around how many treatments the condition actually needs rather than around the sticker price.

Check current price on Amazon (20cm Loop) → · 10cm Loop → (affiliate links, we may earn a commission, at no extra cost to you). As an Amazon Associate I earn from qualifying purchases.

What "FDA cleared" means here, precisely

This is the part worth slowing down for, because it is also the part every seller repeats without the nuance. Assisi and several veterinary sources describe the Loop as an "FDA-cleared NPAID" (Non-Pharmaceutical Anti-Inflammatory Device). The most specific documentation we could independently locate is a 2016 company press release, which states: "The Loop has been cleared by the FDA for treating post-operative pain and edema in humans." We could not independently confirm the specific year the underlying human clearance was granted, or verify a connection to any particular inventor, beyond what that release states.

The precision that matters: the FDA does not regulate veterinary devices the way it regulates human medical devices. The 510(k) clearance pathway that produces a specific K-number exists for devices marketed for human patients; a device sold for use on dogs, cats, and horses is not going through that same premarket review, and we could not locate a public FDA 510(k) record (a specific K-number) for an animal-labeled Assisi Loop in the FDA's own releasable database. That does not mean the "FDA cleared" language is invented. It means the clearance history belongs to the human-use tPEMF technology the Loop is built on, not to a separate veterinary-specific FDA review, and a seller who tells you the animal Loop itself carries its own veterinary 510(k) number is overstating what is publicly confirmable.

Practically: treat the Assisi Loop as a well-engineered device built on technology with a real, documented human clearance history, not as a device that has itself been reviewed and approved by the FDA for veterinary use. No PEMF device sold for animals carries that kind of veterinary approval, because that regulatory category does not really exist in the way pet owners assume.

One condition Assisi itself says to avoid

Worth knowing before you order, and easy to miss on the product page: Assisi states that the Loop "can be applied to any animal, regardless of species, with any inflammatory condition," and then adds, verbatim, "Out of an abundance of caution, we do not recommend using the Assisi LOOP for pets with hemangiosarcoma." That carve-out is the manufacturer's own, not ours, and it is a good reason to tell your veterinarian you are considering a Loop rather than starting one on an undiagnosed mass or swelling. If your animal has been diagnosed with hemangiosarcoma, or is being worked up for it, ask your vet before you use a Loop at all.

What the evidence supports

Assisi's own product page describes the Loop as "backed by years of peer-reviewed clinical research" and states the company has treated "more than 50,000 pets" to date, though it does not cite specific studies by name on that page. Assisi separately lists the Loop as usable across a wide range of conditions, from post-surgical recovery to soft-tissue injury to osteoarthritis. That is a broader claimed evidence base than most consumer PEMF brands state, because it draws on research tied to the human tPEMF technology as well as veterinary case use, but it is the brand's own summary, not an independent literature review. It is still not a guarantee: individual results vary by animal, condition, and consistency of use, and a Loop is a complement to veterinary care, not a substitute for diagnosis. Our how does PEMF therapy work explainer covers the general mechanism in more depth.

Real buyer signal on Amazon

Our own September 2026 survey of high-ticket PEMF products on Amazon recorded the Assisi Loop 2.0 (20cm) with one of the higher rating counts in that set. We flag that cautiously rather than as a precise number, because the same survey turned out to have duplicated rating counts between two listings that are not the same product, so we do not trust any single figure from it. Treat "a real, established listing with real buyer history" as the takeaway rather than a number. Note also that the separate EquiLOOP listing is much newer and has only a handful of ratings so far, and they are mixed, so the Loop's buyer history does not transfer to it. We do not restate Amazon's exact star rating or price here (per Amazon's own program policies, that number is not something we display, and it changes constantly); check the current rating and price directly on the product page before buying.

Who it fits

A single Assisi LOOP or EquiLOOP ($329): the right starting point if you have one injury site, one animal, and want the lowest-cost way to try tPEMF with a technology base that has real clinical history behind it, whether that animal is a dog, cat, or horse. Budget for it as about 150 treatments rather than as a permanent purchase, and check with your vet first if hemangiosarcoma is in the picture.

The LOOP Lounge ($949 to $1,999): the right choice if you want whole-body coverage on a dog or cat rather than one spot, and are comfortable paying combination-mat-level prices for it.

Look elsewhere if: you need a device built for daily, whole-horse use across the back, shoulders, neck, and all four legs at once (a proper equine PEMF blanket, covered in our PEMF for horses guide, fits that job better than one Loop would), or you want whole-body mat coverage instead of a single targeted spot (see our OMI PEMF mat review for that format).

How the Assisi Loop compares

vs a full equine PEMF blanket (OMI Horses, Activo-Med, Respond Systems): the Loop is a single-site tool; a blanket system covers the whole horse's back, shoulders, neck, and legs at once for daily rehab use. See our PEMF for horses guide for the blanket-tier options and their prices.
vs OMI's consumer mat: OMI's full-body mat ($900 to $1,350) is a whole-body relaxation mat; the Loop is a targeted device for one injury or area at a time and costs far less to start with. See our OMI PEMF mat review.
vs the OlyLife Tera P90: OlyLife's device (from around $1,000) is a human-use handheld PEMF-plus-terahertz wand, not built or marketed for animals. The two devices do not really compete; they serve different species and different use cases. See our OlyLife Tera P90 review.

Verdict

The Assisi Loop earns its reputation: a simple, well-priced ($329) device built on a PEMF technology base with a real, documented human FDA clearance history, and a long-established Amazon listing with genuine buyer history behind it. Two caveats that change the math rather than the verdict: it is a consumable, roughly 150 treatments on a battery that cannot be replaced, so price it per session rather than per unit; and Assisi itself advises against using it on pets with hemangiosarcoma. The other honest caveat is regulatory precision, not product quality: the "FDA cleared" language describes the underlying human tPEMF technology's history, not a separate veterinary-specific clearance with its own public K-number, and no PEMF device sold for animals carries that kind of veterinary approval today. Buy a single Loop or EquiLOOP for one animal or one injury site with realistic expectations; step up to the LOOP Lounge for whole-body coverage on a dog or cat, or to a full equine blanket system for a horse that needs daily, whole-body use.

Frequently asked questions

Is the Assisi Loop FDA approved? "Approved" is the wrong word for any device in this category. A 2016 company press release states the underlying human tPEMF technology "has been cleared by the FDA for treating post-operative pain and edema in humans" (a 510(k) clearance, not the stricter "approval" pathway); we could not independently confirm the specific year that human clearance was first granted. We could not confirm a separate, animal-specific FDA clearance record with its own K-number, and the FDA does not review veterinary devices the way it reviews human ones. Treat the clearance history as belonging to the underlying technology, not to a veterinary-specific approval.

How much does the Assisi Loop cost? As verified on Assisi's own store September 20, 2026: a single Loop or EquiLOOP (10cm or 20cm) is $329. The LOOP Lounge full-body system runs $949 (Small) to $1,999 (Large). DentaLOOP (device only) is $149.

Is the EquiLOOP different from the regular Loop? No. It is the same $329 device, sized and marketed for horses. The size (10cm vs 20cm) is the actual variable, not the species label on the box.

How long does an Assisi Loop last? Per Assisi's own FAQ: approximately 150 15-minute treatments, and the battery cannot be recharged or replaced, so the unit's life is the battery's life. Assisi says one Loop 2.0 lasts anywhere from 3 weeks to 6 months depending on the condition and how many treatments a day it needs, and that letting the Loop rest two hours between treatments tends to yield more than the stated minimum. Treat it as a consumable and budget accordingly.

Are there any animals Assisi says not to use the Loop on? Yes, one. Assisi says the Loop can be applied to any animal with any inflammatory condition, but adds that "out of an abundance of caution, we do not recommend using the Assisi LOOP for pets with hemangiosarcoma." Ask your veterinarian before using it on an animal diagnosed with, or being investigated for, that condition.

Does the Assisi Loop actually work? Assisi's own product page describes the Loop as backed by years of peer-reviewed clinical research and cites more than 50,000 pets treated, without naming specific studies on that page. That is a broader claimed evidence base than most consumer PEMF brands state, but it is the brand's own summary. It is not a proven cure for any condition, and results vary by animal and condition. Use it alongside, not instead of, your veterinarian's guidance.

Affiliate disclosure: We earn a commission on some links on this page, and Matt is a registered OlyLife distributor. Commissions never change what the research says about a device. If you buy an Assisi Loop through the Amazon links on this page, we may earn a commission at no extra cost to you. As an Amazon Associate I earn from qualifying purchases. See our affiliate disclosure.

Assisi Loop Review (2026): Pricing and FDA Status